Jesus M, Martins AP, Gallardo E, Silvestre S. Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology. J Anal Methods Chem. 2016;2016:4156293. doi: 10.1155/2016/4156293. Epub 2016 Dec 28. PMID: 28116217; PMCID: PMC5225340.
clear skin x cycle
Aloe vera
Sánchez M, González-Burgos E, Iglesias I, Gómez-Serranillos MP. Pharmacological Update Properties of Aloe Vera and its Major Active Constituents. Molecules. 2020 Mar 13;25(6):1324. doi: 10.3390/molecules25061324. PMID: 32183224; PMCID: PMC7144722.
Fox LT, Gerber M, du Preez JL, du Plessis J, Hamman JH. Skin permeation enhancement effects of the gel and whole-leaf materials of Aloe vera, Aloe marlothii and Aloe ferox. J Pharm Pharmacol. 2015 Jan;67(1):96-106. doi: 10.1111/jphp.12311. Epub 2014 Sep 5. PMID: 25196486.
Capryloyl Salicylsäure
Oresajo C, Yatskayer M, Hansenne I. Clinical tolerance and efficacy of capryloyl salicylic acid peel compared to a glycolic acid peel in subjects with fine lines/wrinkles and hyperpigmented skin. J Cosmet Dermatol. 2008 Dec;7(4):259-62. doi: 10.1111/j.1473-2165.2008.00403.x. PMID: 19146601.
Curcumin-Derivat
Zia A, Farkhondeh T, Pourbagher-Shahri AM, Samarghandian S. The role of curcumin in aging and senescence: Molecular mechanisms. Biomed Pharmacother. 2021 Feb;134:111119. doi: 10.1016/j.biopha.2020.111119. Epub 2020 Dec 24. PMID: 33360051.
Glycerin
Fluhr JW, Darlenski R, Surber C. Glycerol and the skin: holistic approach to its origin and functions. Br J Dermatol. 2008 Jul;159(1):23-34. doi: 10.1111/j.1365-2133.2008.08643.x. Epub 2008 Jul 1. PMID: 18510666.
Verdier-Sévrain S, Bonté F. Skin hydration: a review on its molecular mechanisms. J Cosmet Dermatol. 2007 Jun;6(2):75-82. doi: 10.1111/j.1473-2165.2007.00300.x. PMID: 17524122.
Glycyrrhetinsäure
Murray MT. Glycyrrhiza glabra (Licorice). Textbook of Natural Medicine. 2020 : 641–647.e3.
Pastorino G, Cornara L, Soares S, Rodrigues F, Oliveira MBPP. Liquorice (Glycyrrhiza glabra): A phytochemical and pharmacological review. Phytother Res. 2018 Dec;32(12):2323-2339. doi: 10.1002/ptr.6178. Epub 2018 Aug 17. PMID: 30117204; PMCID: PMC7167772.
Hyaluronsäure
Verdier-Sévrain S, Bonté F. Skin hydration: a review on its molecular mechanisms. J Cosmet Dermatol. 2007 Jun;6(2):75-82. doi: 10.1111/j.1473-2165.2007.00300.x. PMID: 17524122.
Isostearyl Isostearat
Dederen JC, Chavan B, Rawlings AV. Emollients are more than sensory ingredients: the case of isostearyl isostearate. Int J Cosmet Sci. 2012 Dec;34(6):502-10. doi: 10.1111/j.1468-2494.2012.00744.x. PMID: 22913650.
Niacinamid
https://www.researchgate.net/profile/Paul-Matts/publication/286270242_A_Review_of_the_range_of_effects_of_niacinamide_in_human_skin/links/57601eef08ae2b8d20eb27ba/A-Review-of-the-range-of-effects-of-niacinamide-in-human-skin.pdf?ref=myskintips.com
Madaan P, Sikka P, Malik DS. Cosmeceutical Aptitudes of Niacinamide: A Review. Recent Adv Antiinfect Drug Discov. 2021;16(3):196-208. doi: 10.2174/2772434416666211129105629. PMID: 34844552.
OLT®
G. Fabrizio, S. D. Randazzo, A. Cardillo, L. Tiberi und P. Morganti, Safety and efficacy of a lamellar phosphatidylcholine emulsion to treat mild-to-moderate inflammatory acne, SÖFW-Journal 125 (6), 12-14 (1999).
Rotklee
Antonescu Mintas AI, Miere Groza F, Fritea L, Ganea M, Zdrinca M, Dobjanschi L, Antonescu A, Vicas SI, Bodog F, Sindhu RK, Cavalu S. Perspectives on the Combined Effects of Ocimum basilicum and Trifolium pratense Extracts in Terms of Phytochemical Profile and Pharmacological Effects. Plants (Basel). 2021 Jul 7;10(7):1390. doi: 10.3390/plants10071390. PMID: 34371593; PMCID: PMC8309466.
Mohsen A, Fatemeh K, Leila N, Mona P, Mohammad Z, Mozafar K. Pharmacological and therapeutic properties of the Red Clover (Trifolium pratense L.): an overview of the new finding. J Tradit Chin Med. 2021 Aug;41(4):642-649. doi: 10.19852/j.cnki.jtcm.20210324.001. PMID: 34392659.
Troxerutin
Lee KS, Cha HJ, Lee GT, Lee KK, Hong JT, Ahn KJ, An IS, An S, Bae S. Troxerutin induces protective effects against ultraviolet B radiation through the alteration of microRNA expression in human HaCaT keratinocyte cells. Int J Mol Med. 2014 Apr;33(4):934-42. doi: 10.3892/ijmm.2014.1641. Epub 2014 Feb 3. PMID: 24503859.
Zink
Stamatiadis D, Bulteau-Portois MC, Mowszowicz I. Inhibition of 5 alpha-reductase activity in human skin by zinc and azelaic acid. Br J Dermatol. 1988 Nov;119(5):627-32. doi: 10.1111/j.1365-2133.1988.tb03474.x. PMID: 3207614.
grow x cycle
Aloe vera
Fox LT, Gerber M, du Preez JL, du Plessis J, Hamman JH. Skin permeation enhancement effects of the gel and whole-leaf materials of Aloe vera, Aloe marlothii and Aloe ferox. J Pharm Pharmacol. 2015 Jan;67(1):96-106. doi: 10.1111/jphp.12311. Epub 2014 Sep 5. PMID: 25196486.
Lourith N, Kanlayavattanakul M. Hair loss and herbs for treatment. J Cosmet Dermatol. 2013 Sep;12(3):210-22. doi: 10.1111/jocd.12051. PMID: 23992163.
Brennnessel
Pekmezci E, Türkoğlu M. URTICA DIOICA EXTRACT DOWNREGULATES THE GENE EXPRESSION OF 5Α-RII IN HACAT CELLS: POSSIBLE IMPLICATIONS AGAINST ANDROGENIC SKIN DISEASES. Georgian Med News. 2023 Jan;(334):6-9. PMID: 36864786.
CapixylTM und Capigen
Loing E, Lachance R, Ollier V, Hocquaux M. A new strategy to modulate alopecia using a combination of two specific and unique ingredients. J Cosmet Sci. 2013 Jan-Feb;64(1):45-58. PMID: 23449130.
Evans BA, Griffiths K, Morton MS. Inhibition of 5 alpha-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoids. J Endocrinol. 1995 Nov;147(2):295-302. doi: 10.1677/joe.0.1470295. PMID: 7490559.
Olsen EA, Hordinsky M, Whiting D, Stough D, Hobbs S, Ellis ML, Wilson T, Rittmaster RS; Dutasteride Alopecia Research Team. The importance of dual 5alpha-reductase inhibition in the treatment of male pattern hair loss: results of a randomized placebo-controlled study of dutasteride versus finasteride. J Am Acad Dermatol. 2006 Dec;55(6):1014-23. doi: 10.1016/j.jaad.2006.05.007. PMID: 17110217.
Sharquie KE, Al-Obaidi HK. Onion juice (Allium cepa L.), a new topical treatment for alopecia areata. J Dermatol. 2002 Jun;29(6):343-6. doi: 10.1111/j.1346-8138.2002.tb00277.x. PMID: 12126069.
Matsuda H, Yamazaki M, Asanuma Y, Kubo M. Promotion of hair growth by ginseng radix on cultured mouse vibrissal hair follicles. Phytother Res. 2003 Aug;17(7):797-800. doi: 10.1002/ptr.1241. PMID: 12916080.
Stamatiadis D, Bulteau-Portois MC, Mowszowicz I. Inhibition of 5 alpha-reductase activity in human skin by zinc and azelaic acid. Br J Dermatol. 1988 Nov;119(5):627-32. doi: 10.1111/j.1365-2133.1988.tb03474.x. PMID: 3207614.
D-Panthenol
Shin JY, Kim J, Choi YH, Kang NG, Lee S. Dexpanthenol Promotes Cell Growth by Preventing Cell Senescence and Apoptosis in Cultured Human Hair Follicle Cells. Curr Issues Mol Biol. 2021 Sep 28;43(3):1361-1373. doi: 10.3390/cimb43030097. PMID: 34698060; PMCID: PMC8929036.
Grüner Tee
Nualsri C, Lourith N, Kanlayavattanakul M. Development and clinical evaluation of green tea hair tonic for greasy scalp treatment. J Cosmet Sci. 2016 May-Jun;67(3):161-66. PMID: 29394016.
Lourith N, Kanlayavattanakul M. Hair loss and herbs for treatment. J Cosmet Dermatol. 2013 Sep;12(3):210-22. doi: 10.1111/jocd.12051. PMID: 23992163.
Davis SL, Marsh JM, Kelly CP, Li L, Tansky CS, Fang R, Simmonds MSJ. Protection of hair from damage induced by ultraviolet irradiation using tea (Camellia sinensis) extracts. J Cosmet Dermatol. 2022 May;21(5):2246-2254. doi: 10.1111/jocd.14387. Epub 2021 Aug 20. PMID: 34416057.
Kamille
Miraj S, Alesaeidi S. A systematic review study of therapeutic effects of Matricaria recuitta chamomile (chamomile). Electron Physician. 2016 Sep 20;8(9):3024-3031. doi: 10.19082/3024. PMID: 27790360; PMCID: PMC5074766.
Huh S, Lee J, Jung E, Kim SC, Kang JI, Lee J, Kim YW, Sung YK, Kang HK, Park D. A cell-based system for screening hair growth-promoting agents. Arch Dermatol Res. 2009 Jun;301(5):381-5. doi: 10.1007/s00403-009-0931-0. Epub 2009 Mar 11. PMID: 19277688.
Kerazyme Protect
https://activeconceptsllc.com/products/ac-kerazyme/
Rosmarin
Panahi Y, Taghizadeh M, Marzony ET, Sahebkar A. Rosemary oil vs minoxidil 2% for the treatment of androgenetic alopecia: a randomized comparative trial. Skinmed. 2015 Jan-Feb;13(1):15-21. PMID: 25842469.
Murata K, Noguchi K, Kondo M, Onishi M, Watanabe N, Okamura K, Matsuda H. Promotion of hair growth by Rosmarinus officinalis leaf extract. Phytother Res. 2013 Feb;27(2):212-7. doi: 10.1002/ptr.4712. Epub 2012 Apr 20. PMID: 22517595.
Sägepalmenfrucht
Murugusundram S. Serenoa Repens: Does It have Any Role in the Management of Androgenetic Alopecia? J Cutan Aesthet Surg. 2009 Jan;2(1):31-2. doi: 10.4103/0974-2077.53097. PMID: 20300369; PMCID: PMC2840915.
Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med. 2002 Apr;8(2):143-52. doi: 10.1089/acm.2002.8.143. Erratum in: J Altern Complement Med. 2006 Mar;12(2):199. PMID: 12006122.
Rossi A, Mari E, Scarno M, Garelli V, Maxia C, Scali E, Iorio A, Carlesimo M. Comparitive effectiveness of finasteride vs Serenoa repens in male androgenetic alopecia: a two-year study. Int J Immunopathol Pharmacol. 2012 Oct-Dec;25(4):1167-73. doi: 10.1177/039463201202500435. PMID: 23298508.
Schachtelhalm
Chaiyana W, Punyoyai C, Somwongin S, Leelapornpisid P, Ingkaninan K, Waranuch N, Srivilai J, Thitipramote N, Wisuitiprot W, Schuster R, Viernstein H, Mueller M. Inhibition of 5α-Reductase, IL-6 Secretion, and Oxidation Process of Equisetum debile Roxb. ex Vaucher Extract as Functional Food and Nutraceuticals Ingredients. Nutrients. 2017 Oct 10;9(10):1105. doi: 10.3390/nu9101105. PMID: 28994714; PMCID: PMC5691721.